Providing a clear choice for your bone regeneration needs, ProteiOS possesses an array of osteoinductive, chemotactic, angiogenic and mitogenic growth factors that can be added to enhance a surgeon's scaffold of choice. 

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  • More than just a single growth factor or peptide, ProteiOS contains over 600 growth factors, including, but not limited too, established amounts of BMP-2, BMP-4, BMP-6, BMP-7, BMP-9, PDGF-BB, TGF-β and VEGF.[1]
  • Sustained release of growth factors compared to the burst release of rhBMP-2 seen with Infuse.[7,8]
  • Highest non-recombinant BMP-2 content on the market.[1-5]
  • Allows a surgeon to use their scaffold of choice.

OsteoMEM is Biologica's ultra porous shape-memory scaffold with a 'first of its kind', unique antibacterial feature. OsteoMEM’s shape, degradation, strength, and pore size, can all be controlled during the initial fabrication process.

 

OsteoMEM is currently not available for sale in the United States.

OsseoGEN is Biologica's cell-based matrix utilizing Biologica's proprietary tissue processing method. OsseoGEN continues Biologica's ability of processing unique products with increased levels of osteoinductive, chemotactic, angiogenic and mitogenic growth factors.​

Osteoconductivity 

Mineralized cancellous bone is combined with demineralized cortical bone fibers providing an environment that promotes cell attachment, proliferation, and tissue growth.

Osteoinductivity

Demineralized cortical fibers are processed with a process validated to generate fibers with osteoinductive potential along with elevated osteoinductive growth factors due to our proprietary process

Osteogenicity

Mineralized cancellous bone contains attached progenitor and bone cells. Cells are not only ensured to be viable but also are measured for activity confirming their metabolic activity.

Growth Factor Enrichment​

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OsseoGEN is processed using a novel patented process that better preserves the growth factor content found in the donor tissue. Intracellular growth factors are harvested during the processing and delivered bound to the extracellular matrix (ECM) of the bone tissue.


The OsseoGEN process results in higher osteoinductive, chemotactic, angiogenic, and mitogenic growth factors than competitive Cellular Bone Matrices (CBMs)